![]() ![]() ![]() Based on collected information, they conducted a city-level multi-variant, age-structured modeling analysis to estimate the infection and immune evasion ability changes for the B.1.526 variant. The scientists utilized a network model-inference system to estimate the transmission dynamics of SARS-CoV-2 and population-level variables and parameters in New York City. In the current study, the scientists have analyzed multiple epidemiological and population datasets collected in New York City and performed mathematical modeling to determine the transmission rate, immune evasion ability, and infection fatality risk of the B.1.526 variant. In contrast, evidence indicates that the variant does not increase the risk of breakthrough infections in vaccinated or previously infected individuals. Later, the variant has been detected in all 52 states in the United States, as well as in 27 countries across the world.Īs observed in a laboratory-based study, this variant is modestly resistant to neutralization by therapeutic monoclonal antibodies and vaccine/infection-induced antibodies. The B.1.526 variant of SARS-CoV-2, also known as the lota variant, was first identified in New York City in November 2020. Because of increased infectivity and pathogenicity, some of these variants have been designated as Variants of Concern (VOC) or Variants of Interest (VOI) by the World Health Organization (WHO). ![]() With the progression of the coronavirus disease 2019 (COVID-19) pandemic, several new variants of SARS-CoV-2 have been identified. The study is currently available on the medRxiv* preprint server. The findings reveal that the variant has considerably higher transmissibility and immune escape potential than previously circulating variants and that it can increase the infection fatality rate by 62% - 82% among older adults. A study conducted at the New York City Department of Health and Mental Hygiene, USA, and the Mailman School of Public Health, Columbia University, USA, has determined the transmission rate, immune escape ability, and infection fatality rate of the B.1.526 variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). ![]()
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